If you plan on using Qubes OS, it’s really only the main board you need to worry about. You can check the official Qubes OS forum, there is a section where people post hardware compatibility reports, it’s a good place to find hardware that is confirmed to be working.
The AMD main boards typically have more USB controllers, which is a pretty big advantage when using Qubes OS. Having 3 or 4 on-board controllers gives you a lot of freedom, when using USB devices. Not a much have, but it really is a huge QOL improvement.
Intel’s asymmetrical chiplet design can be a little annoying when running Qubes OS. Xen can use both the P and E cores, but can’t do any form of hybrid scheduling. It’s also not possible to change the scheduler granularity to core level when using an asymmetric CPU, this is a minor issue and really only matters is you decide to run Qubes OS with hyper threading enabled.