This isn’t the form of total hardware isolation that folks in the digital minimalism space for privacy/security are after (I don’t think). If they were, they’d simply use or advocate for hot-swap-able storage instead? I wrote on GrapheneOS forums (can’t find the link) about why even hardware-assisted virtualization (specifically in the context of pkvm that GrapheneOS team is working on) isn’t isolation enough for folks who practice digital minimalism (of needing one device per context) for security & privacy purposes (like folks in high-risk situations & professions).
You can call having a bed room, a living room, a home office, a kitchen … all some form of isolation even if it is all behind the same door, but in reality, having a vacation home, having a workplace to go to, having meals at diners are very different kinds of “isolation”, if we can call it that.