I’m not a pro in networking, but my understanding is that if you’re using an actual VPN (over OpenVPN/Wireguard/IPSec/IKEv2/etc protocol) everything should tunnel to your exit point and get routed anywhere from there. At least that’s the conclusion i came to in my experience.
If you’re using a commercial VPN service that should be the case, but if you’re self-hosting there might be complications if you deviate from the defaults.
I’d be glad to be fixed if i’m mistaken.